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A similar dietary supplementation was also found to decrease the phosphorylation of PPARγ and nuclear factor E2-related factor 2 (Nrf2) and induce upregulation of their downstream targets including α-glutathione S-transferase (GSTα) and adenosine triphosphate-binding cassette transporter A1 (ABCA1) through inhibition of matrix metalloproteinase-1 (MMP-1) (Bozaykut et al., 2017)