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qRT-PCR analysis of metastatic lymph nodes from CRC patients revealed a significantly higher expression of AKR1C3 especially in Dukes’ stage C compared to controls indicating that expression of AKR1C3 is a reliable marker for lymph node metastasis [68]

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Fluorimetric determination of nitrite in the presence of 2,3-diaminonaphthalene Nitrite was determined using 12.6 µM 2,3-diaminonaphthalene (DAN) to form the fluorescent product 1-( H )-naphthotriazole [33]